Searchable abstracts of presentations at key conferences in endocrinology

ea0007p20 | Cytokines and growth factors | BES2004

Glucocorticoids suppress macrophage migration inhibitory factor (MIF) expression in a cell-type specific manner

Alourfi Z , Donn R , Stevens A , Ray D

Aim: To investigate glucocorticoid (Gc) regulation of MIFBackground: MIF is a potent proinflammatory cytokine involved in inflammatory arthritis. Previous work suggested that MIF was induced by low concentrations of Gc, and may counteract their anti-inflammatory effect. The relationship between MIF and Gc has not been investigated in human cells.Methods: The human cell lines CEMC7A (T-lymphoblast) and A549 (lung epithelial) were us...